No. I have had 9 of them. It is the prep that is awful. But as far as the actual procedure, you shouldn’t feel a thing. I have had just a little soreness (on the insides) from one time they took 20 punch biopsies, but that is rare. They will probably take just a little test biopsy from 4 or so different areas so that they can test for Chron’s, UC, etc. It’s OK to be nervous, but quite honestly I have felt like a million bucks afterwards most of the time.
Most of the time they give you medicine that puts you out and you wake up and it’s over